Stressed MSA-Alexa700 formed fluorescent “hot-spots” in lungs, livers and spleens of mice injected IP and IV.

<p>A) IV injection of stressed MSA-Alexa700 resulted in the formation of fluorescent “hotspots” in the lungs and spleens. B) In livers and spleens of animals IP injected with stressed protein clumps of highly fluorescent signal were observed.